Allvivo Vascular (AVI) is a provider of Biomimetic Surface Coating technologies for the cardiovascular device industry. We have a broad platform technology that can be used to improve the performance of a variety of medical devices. By applying our coating technology, you can differentiate your device to obtain a competitive advantage, expand your market share and increase revenues. Coatings can also be employed to expand the indications for which a device may be used and thereby expand the size of the target market.

Our lead product application is a next generation coating for stents to reduce restenosis. This coating provides important advantages over drug eluting stents and is expected to increase the safety and efficacy of coated stents while eliminating the need to extend costly antiplatelet therapy beyond one month. AVI has developed this coating through the preclinical stage and is preparing to initiate a FIM study.

In addition to coronary and peripheral stents, AVI’s Biomimetic coatings can be used to improve the performance of many types of devices such as pace maker leads, heart assist devices, vascular grafts, AV access grafts, cardiopulmonary bypass circuits and indwelling blood gas sensors.

There are four main ways that AVI can work with you to improve your products:

• We can help you apply our hemocompatible and anti-inflammatory coating based on EGAP and factor H to your existing products

• If there is a therapeutic or biologically active entity that is of interest to your company we can help you apply that entity to device surfaces using our proprietary polymer coating technology.

• If there is a specific device or disease related challenge that you would like to target with a surface coating, we can potentially help you select and develop a coating to solve that problem.

• We are currently developing novel antibacterial coatings that will be available for licensing.

AVI licenses its patented surface modification technologies to medical device and life science companies. We are flexible in our approach to business development and are willing to work with you to develop a relationship that is compatible with your company’s goals and product commercialization strategy. If you have a medical device that might benefit from our coating technology, we would welcome an opportunity to talk with you. Please contact:

Jennifer Neff, Ph.D., Chief Technology Officer

Email: neff@allvivo.com

Phone: (949) 716-6478